Grayscale 2025 Q1 Top Picks: 20 Tokens with High Growth Potential

By: blockbeats|2024/12/30 11:15:04
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Original Title: Grayscale Research Insights: Crypto Sectors in Q1 2025
Original Source: Grayscale Research
Original Translation: Golem, Odaily Planet Daily

Summary:

· The crypto market saw a significant surge in Q4 2024, with the FTSE/Grayscale Crypto Sectors Index demonstrating strong market performance. The rally largely reflected the market's positive response to the outcome of the U.S. presidential election.

· Competition in the smart contract platform sector remains intense. The price performance of sector leader Ethereum has lagged behind its second-largest competitor Solana, and investors are increasingly focusing on other Layer 1 networks such as Sui and The Open Network (TON).

· Grayscale Research updated the Top 20 token list, representing diversified assets in the cryptocurrency industry that may have high potential in the next quarter. New assets added in Q1 2025 include HYPE, ENA, VIRTUAL, JUP, JTO, and GRASS. All assets in the Top 20 list exhibit high price volatility and should be considered high-risk.

Grayscale Crypto Sectors Index

The Grayscale Crypto Sectors provide a comprehensive framework for understanding the range of investable digital assets and their relationship to underlying technologies. Building on this framework and in collaboration with FTSE Russell, Grayscale has developed the FTSE Grayscale Crypto Sectors Index series to measure and monitor crypto assets (Figure 1). Grayscale Research incorporates this index into its analysis of the digital asset market.

Grayscale 2025 Q1 Top Picks: 20 Tokens with High Growth Potential

Figure 1: Positive Returns of the 2024 Grayscale Crypto Sectors Index

Cryptocurrency valuations soared in the fourth quarter of 2024, primarily due to the market's positive reaction to the U.S. election results. According to the Crypto Sector Market Index (CSMI), the industry's total market cap increased from $1 trillion to $3 trillion in this quarter. Figure 2 compares the total cryptocurrency market cap to various traditional public and private market asset categories. For instance, the current market value of the digital asset industry is roughly equivalent to the global inflation-linked bond market – more than double the U.S. high-yield bond market, yet still significantly below the global hedge fund industry or the Japanese stock market.

Figure 2: Cryptocurrency Market Cap Increases by $1 Trillion in Q4 2024

Due to the valuation increase, many new tokens met the inclusion criteria of Grayscale's Crypto Sectors framework (which sets a minimum market cap requirement of $1 billion for most tokens). In this quarter's rebalance, Grayscale added 63 new assets to the index series, now totaling 283 tokens. The consumer and culture sectors saw the most new token additions, reflecting the ongoing strong performance of meme coins and the appreciation of various assets related to gaming and social media.

By market cap, the largest new asset in Crypto Sectors is Mantle, an Ethereum Layer 2 protocol, which now meets the minimum liquidity requirement (for more detailed information on Grayscale index inclusion criteria, please refer to here).

Smart Contract Platform Competition

The smart contract platform space may be the most fiercely competitive submarket in the digital asset industry. While 2024 was a milestone year for the leader in this space, Ethereum—receiving approval for a U.S. exchange-traded product (ETP) and undergoing significant upgrades—ETH's performance lags behind some competitors like Solana, the second-largest asset by market cap in the space. Investors are also turning their attention to other L1 networks, including high-performance blockchains like Sui and the blockchain TON integrated with the Telegram platform.

When building infrastructure for application developers, architects of smart contract blockchains face a variety of design choices. These design choices impact the three factors that make up the "blockchain trilemma": network scalability, network security, and network decentralization. For example, prioritizing scalability often manifests as high transaction throughput and low fees (e.g., Solana), while prioritizing decentralization and network security may result in lower throughput and higher fees (e.g., Ethereum). These design choices lead to different block times, transaction throughputs, and average transaction fees (Figure 3).

Figure 3: Smart Contract Platforms Have Different Technical Features

Regardless of design choices and network trade-offs, smart contract platforms derive their value through network fee revenue. While other metrics such as total TVL are also crucial, fee revenue can be seen as a primary driver of token value accumulation in this market segment (related reading: The Value War in Smart Contract Platforms).

As shown in Figure 4, there is a statistical relationship between smart contract platform fee revenue and market capitalization. The stronger the network's ability to generate fee revenue, the greater its ability to pass value to the network in the form of token burning or staking rewards. This quarter, the Top 20 token list listed by Grayscale Research includes some smart contract platform tokens: ETH, SOL, SUI, and OP.

Figure 4: All smart contract platforms are competing for fee revenue

Grayscale Research Top 20 Token List

Each quarter, the Grayscale Research team analyzes hundreds of digital assets to provide insights for the rebalancing process of the FTSE/Grayscale Crypto Sectors index series. Following this process, Grayscale Research generates a list of the top 20 assets within the Crypto Sectors domain. The top 20 represent diversified assets across Crypto Sectors and these assets may have high potential in the upcoming quarter (Figure 4). The selection of this list combines a range of factors, including network growth/adoption, upcoming catalysts, sustainability of fundamentals, token valuation, token supply inflation, and potential tail risks.

In Q1 2025, Grayscale will focus on tokens that are involved in at least one of the following three core market themes:

· The U.S. election and its potential impact on industry regulation, especially in decentralized finance (DeFi) and staking;

· Continued breakthroughs in decentralized AI technology and the use of AI agents in blockchain;

· Growth of the Solana ecosystem.

Based on these themes, the following six assets have been added to the Top 20 list for the first quarter of 2025:

1. Hyperliquid (HYPE): Hyperliquid is an L1 blockchain designed to support on-chain financial applications. Its primary application is a decentralized exchange (DEX) for perpetual futures with a fully on-chain order book.

2. Ethena (ENA): The Ethena protocol has evolved into the new stablecoin USDe, primarily collateralized by Bitcoin and Ethereum hedge positions. Specifically, the protocol holds long positions in Bitcoin and Ether as well as short positions in perpetual futures contracts of the same assets. The staked version of this token provides yield through the price differential between spot and futures.

3. Virtual Protocol (VIRTUAL): Virtual Protocol is a platform built on the Ethereum L2 network Base to create AI agents. These AI agents are designed to mimic human decision-making and autonomously perform tasks. The platform allows for the creation and co-ownership of tokenized AI agents that can interact with their environment and other users.

4. Jupiter (JUP): Jupiter is a top-tier DEX aggregator on Solana with the highest TVL in the network. With retail traders increasingly entering the cryptocurrency market through Solana and speculative activities surrounding Solana-based memecoins and AI agent tokens on the rise, we believe Jupiter is well-positioned to capitalize on this growing market.

5. Jito (JTO): Jito is a liquidity protocol on Solana. Jito has seen significant adoption over the past year and boasts the best financials in the cryptocurrency space, with fee revenue surpassing $5.5 billion in 2024.

6. Grass (GRASS): Grass is a decentralized data network that rewards users for sharing their unused internet bandwidth through a Chrome extension. This bandwidth is used to scrape online data, which is then sold to AI companies and developers for training machine learning models, effectively enabling web data scraping while compensating users.

Figure 5: Top 20 Additions including DeFi Applications, AI Agents, and the Solana Ecosystem

Note: Shadow denotes new tokens coming in the upcoming quarter (Q1 2025). "*" denotes sector-related assets not included in the Crypto Sectors index. Data Source: Artemis, Grayscale Investments. Data as of December 20, 2024, for reference only. Assets are subject to change. Grayscale and its affiliates and clients may hold positions in the digital assets discussed in this document. All Top 20 assets are highly price volatile and should be considered high-risk assets.

In addition to the new themes mentioned above, Grayscale remains bullish on themes from the past few quarters, such as Ethereum scaling solutions, tokenization, and Decentralized Physical Infrastructure (DePIN). These themes are still reflected through protocols re-entering the Top 20, such as Optimism, Chainlink, and Helium.

This quarter, we have removed Celo from the Top 20. Grayscale Research continues to be optimistic about these projects and believes they remain integral to the crypto ecosystem. However, the revised Top 20 list may offer a more compelling risk-reward profile in the next quarter.

Investing in crypto assets carries risks, some of which are unique to the asset class, including smart contract vulnerabilities and regulatory uncertainty. Furthermore, all assets in the Top 20 exhibit high volatility and should be considered high-risk, making them unsuitable for all investors. Given the risks of the asset class, any investment in digital assets should be considered in the context of a portfolio and with respect to an investor's financial goals.

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$COIN Joins S&P 500, but Coinbase Isn't Celebrating

On May 13, S&P Dow Jones Indices announced that Coinbase would officially replace Discover Financial Services in the S&P 500 on May 19. While other companies like Block and MicroStrategy, closely tied to Bitcoin, were already part of the S&P 500, Coinbase became the first cryptocurrency exchange whose primary business is in the index. This also signifies that cryptocurrency is gradually moving from the fringes to the mainstream in the U.S.



On the day of the announcement, Coinbase's stock price surged by 23%, surpassing the $250 mark. However, just 3 days later, Coinbase was hit by two consecutive events: a hack where employees were bribed to steal customer data and a demand for a $20 million ransom, and an investigation by the U.S. Securities and Exchange Commission (SEC) into the authenticity of its claim of having over 100 million "verified users" in its securities filings and marketing materials. These two events acted as mini-bombs, and at the time of writing, Coinbase's stock had already dropped by over 7.3%.


Coincidentally, Discover Financial Services, being replaced by Coinbase, can also be considered the "Coinbase" of the previous payment era. Discover is a U.S.-based digital banking and payment services company headquartered in Illinois, founded in 1960. Its payment network, Discover Network, is the fourth largest payment network apart from Visa, Mastercard, and American Express.


In April, after the approval of the acquisition of Discover by the sixth-largest U.S. bank, Capital One, this well-established digital banking company of over 60 years smoothly handed over its S&P 500 "seat" to this emerging cryptocurrency "bank." This unexpected coincidence also portrayed the handover between the new and old eras in Coinbase's entry into the S&P 500, resembling a relay race scene. However, this relay baton also brought Coinbase's accumulated "external troubles and internal strife" to a tipping point.


Side Effects of ETFs


Over the past decade, cryptocurrency exchanges have been the most stable "profit machines." They play a role in providing liquidity to the entire industry and rely on trading fees to sustain their operations. However, with the comprehensive rollout of ETF products in the U.S. market, this profit model is facing unprecedented challenges. As the leader in the "American stack," with over 80% of its business coming from the U.S., Coinbase is most affected by this.



Starting from the approval of Bitcoin and Ethereum spot ETFs, traditional financial capital has significantly onboarded users and funds that originally belonged to exchanges in a more cost-effective, compliant, and transparent manner. The transaction fee revenue of cryptocurrency exchanges has started to decline, and this trend may further intensify in the coming months.


According to Coinbase's 2024 Q4 financial report, the platform's total trading revenue was $417 million, a 45% year-on-year decrease. The contribution of BTC and ETH's trading revenue dropped from 65% in the same period last year to less than 50%.


This decline is not a result of a decrease in market enthusiasm. In fact, since the approval of the Bitcoin ETF in January 2024, the inflow of BTC into the U.S. market has continued to reach new highs, with asset management giants like BlackRock and Fidelity rapidly expanding their management scale. Data shows that BlackRock's iShares Bitcoin ETF (IBIT) alone has surpassed $17 billion in assets under management. As of mid-May 2025, the cumulative net inflow of 11 major institutional Bitcoin spot ETFs on the market has exceeded $41.5 billion, with a total net asset value of $1214.69 billion, accounting for approximately 5.91% of the total Bitcoin market capitalization.


Chart showing the trend of net outflows for Grayscale among the 11 institutions


Institutional investors and some retail investors are shifting towards ETF products, partly due to compliance and tax considerations. On one hand, ETFs have much lower trading costs compared to cryptocurrency exchanges. While Coinbase's spot trading fee rate varies annually in a tiered manner but averages around 1.49%, for example, the management fee for IBIT ETF is only 0.25%, and the majority of ETF institution fees fluctuate around 0.15% to 0.25%.



In other words, the more rational users are, the more likely they are to move from exchanges to ETF products, especially for investors aiming for long-term holdings.


According to multiple sources, several institutions, including VanEck and Grayscale, have submitted applications to the SEC for a Solana (SOL) ETF, with some institutions also planning to submit an XRP ETF proposal. Once approved, this may trigger a new round of fund migration. According to a report submitted by Coinbase to the SEC, as of April, the platform's trading revenue from XRP and Solana accounted for 18% and 10%, nearly one-third of the platform's fee revenue.



However, the Bitcoin and Ethereum ETFs passed in 2024 also reduced the fees for these two tokens on Coinbase from 30% and 15% to 26% and 10%, respectively. If the SOL and XRP ETFs are approved, it will further undermine the core fee revenue of exchanges like Coinbase.


The expansion of ETF products is gradually weakening the financial intermediary status of cryptocurrency exchanges. From their original roles as matchmakers and clearers to now gradually becoming mere "on-ramps and off-ramps" for funds, exchanges are seeing their marginal value squeezed by ETFs.


Robinhood Takes a Stand, Traditional Brokerages Join the Fray


On May 12, 2025, SEC Chairman Paul S. Atkins gave a keynote speech at the Tokenization and Cryptocurrency Working Group roundtable. The theme of his speech revolved around "It is a new day at the SEC," where he indicated that the SEC would not approach enforcement and regulation the same way as before but would instead pave the way for cryptocurrency assets in the U.S. market.



With signs of cryptocurrency compliance such as the SEC's "NEW DAY" declaration, an increasing number of traditional brokerages are attempting to enter the cryptocurrency industry. One of the most representative cases is the well-known U.S. brokerage Robinhood, which began expanding its crypto business in 2018. By the time of its IPO in 2021, Robinhood's crypto business revenue accounted for over 50% of the company, with a significant boost from the Dogecoin "moonshot" promoted by Musk.


In Q1 2025 earnings report, Robinhood showcased strong growth, especially in revenue from cryptocurrency and options trading. Fueled by Trump's Memecoin, cryptocurrency-related revenue reached $250 million, nearly doubling year-over-year. Consequently, Robinhood Gold subscription users reached 3.5 million, a 90% increase from the previous year, with the rapid growth of Robinhood Gold providing the company with a stable source of income.



Meanwhile, RobinHood is actively pursuing acquisitions in the cryptocurrency space. In 2024, it announced a $2 billion acquisition of the long-standing European cryptocurrency exchange Bitstamp. Additionally, Canada's largest cryptocurrency CEX, WonderFi, which recently went public on the Toronto Stock Exchange, also announced its integration with RobinHood Crypto. After obtaining virtual asset licenses in the UK, Canada, Singapore, and other markets, RobinHood has taken a proactive approach in the compliant cryptocurrency trading market.



Furthermore, an increasing number of brokerage firms are exploring the same path. Futu Securities, Tiger Brokers, and others are also dipping their toes into cryptocurrency trading, with some having applied for or obtained the VA license from the Hong Kong SFC. Although their user bases are currently small, traditional brokerages have a natural advantage in user trust, regulatory licenses, and low fee structures. This could pose a threat to native cryptocurrency platforms in the future.



User Data Breach: Is Coinbase Still Secure?


In April 2025, security researchers discovered that some Coinbase user data was leaked on the dark web. While the platform initially responded by attributing it to a "technical misinformation," it still raised concerns among users regarding its security and privacy protection. Just two days before Dow Jones Indexes announced Coinbase's addition to the S&P 500 Index, on May 11, 2025, Coinbase received an email from an unknown threat actor claiming to have obtained customer account information and internal documents, demanding a $20 million ransom to keep the data private. Subsequent investigations confirmed the data breach.


Cybercriminals obtained the data by bribing overseas customer service agents and support staff, mainly in "non-U.S. regions such as India." These agents abused their access to Coinbase's internal customer support system and stole customer data. As early as February this year, blockchain detective ZachXBT revealed on X platform that between December 2024 and January 2025, Coinbase users lost over $65 million to social engineering scams, with the actual amount potentially higher.


Among the victims was a well-known figure, 67-year-old Ed Suman, an established artist in the art world for nearly two decades, having been involved in the creation of artworks such as Jeff Koons' "Balloon Dog" sculpture. Earlier this year, he fell victim to an impersonation scam involving fake Coinbase customer support, resulting in a loss of over $2 million in cryptocurrency. ZachXBT critiqued Coinbase for its inadequate handling of such scams, noting that other major exchanges have not faced similar issues and recommending Coinbase to enhance its security measures.


Amidst a series of ongoing social engineering incidents, although there has not been any impact on user assets at the technical level so far, it has raised concerns among many retail and institutional investors. Especially institutions holding massive assets on Coinbase. Just considering the U.S. BTC ETF institutions, as of mid-May 2025, they collectively hold nearly 840,000 BTC, and 75% of these are custodied by Coinbase. If we price BTC at $100,000, this amount reaches a staggering $63 billion, which is equivalent to the nominal GDP of two Iceland in the year 2024.


Visualization: ChatGPT, Source: Farside


In addition, Coinbase Custody also serves over 300 institutional clients, including hedge funds, family offices, pension funds, and endowments. As of the Q1 2025 financial report, Coinbase's total assets under management (including institutional and retail clients) reached $404 billion. The specific amount of institutional custodied assets was not explicitly disclosed in the latest report, but it should still be over 50% based on the Q4 2024 report.


Visualization: ChatGPT


Once this security barrier is breached, not only could the rate of user attrition far exceed expectations, but more importantly, institutional trust in it would undermine the foundation of its business. Therefore, after a hacking event, Coinbase's stock price plummeted significantly.


CEXs are All in Self-Rescue Mode


Facing a decline in spot trading fee revenue, Coinbase is also accelerating its transformation, attempting to find growth opportunities in derivatives and emerging assets. Coinbase acquired a stake in the options platform Deribit at the end of 2024 and announced the official launch of perpetual contract products in 2025. This acquisition fills in Coinbase's gap in options trading and its relatively small global market share.



Deribit has a strong presence in non-U.S. markets, especially in Asia and Europe. The acquisition has enabled Coinbase to gain a dominant position in bitcoin and ethereum options trading on Deribit, accounting for approximately 80% of the global options trading volume, with daily trading volume remaining above $2 billion.


Meanwhile, 80-90% of Deribit's customer base consists of institutional investors, with their professionalism and liquidity in the Bitcoin and Ethereum options market highly favored by institutions. Coinbase's compliance advantage, coupled with its already robust institutional ecosystem, makes it even more suitable. By using institutions as an entry point, it can face the squeeze from giants like Binance and OKX in the derivatives market.



Facing a similar dilemma is Kraken, which is attempting to replicate Binance Futures' model in non-U.S. markets. Since the derivatives market relies more on professional users, fee rates are relatively higher and stickiness is stronger, making it a significant source of revenue for exchanges. In the first half of 2025, Kraken completed the acquisition of TradeStation Crypto and a futures exchange, aiming to build a complete derivatives trading ecosystem to hedge the risk of declining spot transaction fee income.


With the surge of Memecoin in 2024, Binance, OKX, and various CEX platforms began massively listing small-market-cap, highly volatile tokens to activate active trading users. Due to the wealth effect and trading activity of Memecoins, Coinbase was also forced to join the battle, successively listing popular tokens from the Solana ecosystem such as BOOK OF MEME and Dogwifhat. Although these coins are controversial, they are frequently traded, with fee rates several times higher than mainstream coins, serving as a "blood-boosting" method for spot trading.


However, due to its status as a publicly traded company, this practice is a riskier endeavor for Coinbase. Even in the current crypto-friendly environment, the SEC is still investigating whether tokens like SOL, ADA, and SAND constitute securities.


In addition to the forced transformation strategies carried out by the aforementioned CEXs, they are also starting to lay out RWAs and the most talked-about stablecoin payment fields, such as the PYUSD launched through a collaboration between Coinbase and Paypal, Coinbase's support for the Euro stablecoin EURC by Circle that complies with EU MiCA regulatory requirements, or the USD1 launched through a collaboration between Binance and WIFL. In the increasingly crowded trading field, many CEXs have shifted their focus from just the trading market to the application field.


The golden age of transaction fees has quietly ended, and the second half of the crypto exchange platform game has silently begun.


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